Physical pain has been a part of our lives one way or the other, and people have always resorted to many ways to relieve their pain. 

Quick Facts About Tzact

Generic NameEtoricoxib
Brand Name



Arvincare Pharma

Type of MedicationNonsteroidal anti-inflammatory medication (NSAID)
UsesReduces pain and swelling in joints and muscles associated with: Rheumatoid arthritis, Osteoarthritis, Ankylosing spondylitis, Acute gout, Short-term treatment of moderate pain after dental surgery (for adults 16 years and older)
Mechanism of Action Inhibits COX-2 enzyme, reducing prostaglandins to decrease pain and inflammation
Effectiveness Effective for pain and inflammation management
Dosage FormTablet
Color Varies (white, yellow, brown, etc.)
Available Strength30mg, 60mg, 90mg, 120mg
Dosage Varies by condition; for example, 30mg once daily for osteoarthritis, which may be increased to 60mg if needed
Controlled Substance ClassificationNot a controlled drug
Side Effects Common side effects include: Stomach upset, heartburn, nausea, diarrhea, dizziness. More serious side effects can occur, so consult a doctor for a complete list of potential side effects
PrecautionsNot suitable for everyone, especially those with certain medical conditions or allergies. Consult a doctor before taking Tzact, especially if you have: stomach ulcers or bleeding, heart or kidney problems, high blood pressure, liver disease, are pregnant or breastfeeding
Interactions May interact with other NSAIDs, blood thinners, ACE inhibitors, etc.
AdministrationTake by mouth with or without food. Follow doctor's instructions for dosage and duration of use
Availability  Prescription only
StorageStore at room temperature in a dry place. Keep out of reach of children and pets
Pregnancy Category Category B - No proven risks in humans
Cost• 2,496.00 NGN - 2,992.00 NGN for 10 tablets

• 1.40 GBP - 1.68 GBP for 10 tablets

• 1.75 USD - 2.10 USD for 10 tablets

• 1.63 EUR - 1.95 EUR for 10 tablets

• 12.65 - 15.18 CNY for 10 tablets

Some people even resort to illegal and harmful ways to alleviate their pain like getting pseudo-high on hard drugs like cocaine. 

Others follow normal procedures and use legal medications like painkillers and pain relievers. 

So today, Healthsoothe will not be focusing on cocaine, but on a pain reliever known as Tzact. 

Tzact is among many of the pain relievers out there that people use to alleviate or relieve their physical pains.

So if you are having pains due to arthritis or pains from a post-dental surgery and you are thinking about using Tzact, and you are wondering how safe this drug is, how it works, its benefits, side effects, and other things. 

Then don’t worry, we got you covered here. This article will answer all these questions and more, 


Tzact tablet– What is it?

Tzact - Healthsoothe

Tzact Tablet is a narcotic pain reliever. Tzact Tablet is an Arvincare Pharma trademark of Etoricoxib. 

Etoricoxib is a selective COX-2 inhibitor. COX-2 is an enzyme implicated in pain and inflammation. 

It belongs to the COX-2-selective (coxib) nonsteroidal anti-inflammatory medication class (NSAIDs). The cyclooxygenase-2 (COX-2) selective inhibitors class.

It is primarily used in the treatment of pain. It also belongs to the Sulfone and Pyridine derivatives chemical class and the therapeutic class.

Analgesics for pain and their mode of action include COX-2 Inhibitors that are NSAIDs.

Tzact drug details summary

  • Strength: 30mg, 60mg, 90mg, and 120mg.
  • Color: Varies (From white, yellow, and brown to other colors).
  • Size: Varies (10 -12mm).
  • Shape: Elliptical/oval.
  • Availability: Rx and/or OTC
  • Drug class: Cyclooxygenase-2 (COX-2) selective inhibitors class, Nonsteroidal anti-inflammatory medication class (NSAIDs), Sulfone and Pyridine Derivative chemical class, and the therapeutic class.
  • Pregnancy Category: B - No proven risks to humans.
  • CSA schedule: Not a controlled drug.
  • Labeler/Supplier: Arvincare Pharma.
  • Active ingredients: Salt composition of Etoricoxib.


How does the Tzact tablet work?

Tzact Tablet is a COX-2 inhibitor, which is a kind of nonsteroidal anti-inflammatory medication (NSAID).

It works by preventing the production of particular chemical messengers that cause pain and inflammation (redness and swelling).

Tzact belongs to a class of drugs known as cyclooxygenase-2 (COX-2) selective inhibitors (also known as coxibs).

COX-1 and COX-2 are two related enzymes produced by the body. COX-1, among other things, protects the stomach, while COX-2 is implicated in joint inflammation and discomfort.

Tzact alleviates pain and inflammation by inhibiting COX-2, a biological enzyme. Tzact does not inhibit COX-1, an enzyme that protects the stomach from ulcers.

Other nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit both COX-1 and COX-2.


How should I use the Tzact tablet?

Take this medication at the dosage and for the period prescribed by your doctor. Take it all at once. It should not be chewed, crushed, or broken.

Tzact Tablet may be taken with or without meals, although it is best to take it at the same time every day.

Tzact pills should only be used once per day. You may take your pill with or without food, although taking it without food will cause it to work faster.

If you have arthritis, you will almost certainly need to take medication daily to reduce inflammation and discomfort. 

Tablets come in four different strengths: 30mg, 60mg, 90mg, and 120mg. The strength of the drug is decided by the reason you're taking it.

Dosing instructions for Tzact

  • Dosage for osteoarthritis: The standard dose for osteoarthritis is 30 mg once a day, which may be increased to 60 mg if needed.
  • Dosage for rheumatoid arthritis and ankylosing spondylitis: The usual dose is 60 mg once a day, which may be increased to 90 mg if necessary. If you have acute gout, take one pill each day for up to eight days.
  • Dosage for acute gout: The usual dose is 120 mg once a day for up to eight days.
  • Dosage for pain relief after dental surgery: The standard dose for pain relief following dental surgery is 90 mg once a day for three days.

What if I miss a dose of Tzact?

Nothing much will happen. Just that if you have missed significant doses of the drug, it will not be effective or potent enough to treat you for the ailment you took it for.

Do the following if you have miss dosed;

  • If you forget to take one or more doses: take your next dose at the usual time and in the average amount. Do not take any more than your doctor prescribed.
  • If you miss one dose, skip it and continue with your normal schedule.
  • Do not increase the dosage to catch up with the missed doses.
  • You should consult your doctor on what to do if you don’t know what to do.

What if I overdose on a Tzact tablet?

If you suspect an overdose, contact your doctor immediately. Overdose symptoms include skin rashes, disorientation, chest discomfort, and impaired vision.


What are the benefits or uses of the Tzact tablet?

This drug is mainly used to relieve pain.

Tzact Tablet is prescribed for the short-term treatment of joint and muscular pain, inflammation, and edema.

It works by inhibiting chemical messengers in the brain that alert us to pain.

It may aid with pain relief in illnesses such as rheumatoid arthritis and osteoarthritis, as well as following dental (tooth-related) surgery.

Tzact Tablet reduces inflammation (swelling) and discomfort associated with arthritic conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.

It's also used to relieve pain in the short term during gout episodes and after dental surgery.

To get the most out of it, take it exactly as directed. It is harmful to take more or for a longer period than is necessary.

In general, you should take the lowest effective dosage for the shortest time. This will make it easier for you to go about your regular routines and have a better, more active quality of life.


Are there any side effects of the Tzact tablet?

Most side effects are harmless and will go away as your body adapts to the medication. Consult your doctor if they persist or if you are concerned.

Common and mostly minor side effects of Tzact include;

  • Arrhythmia
  • Oral ulcer
  • Bronchospasm
  • Dizziness
  • Esophagitis
  • Stomach pain
  • Headache
  • Diarrhea
  • Constipation
  • Indigestion

Significant or major side effects of Tzact include;

  • Heartburn
  • Increased liver enzymes
  • Flu
  • Indigestion
  • Palpitations
  • Peripheral edema
  • Flatulence
  • vomiting
  • Weakness
  • Fatigue
  • Bruises
  • Nausea
  • High blood pressure
  • Irregular heartbeat
  • Difficult while breathing
  • Heart rhythm disorders

Tzact may have major negative effects and create serious health concerns. If you are experiencing any of the significant side effects listed above. If you are experiencing any major issues, see your doctor.


How long does it take Tzact to work?

Tzact provided pain alleviation after around 4 hours. It may take a little longer for the whole impact to take effect, and it may vary from person to person.


How long should I take Tzact before it starts working?

Tzact must be taken for the duration prescribed by your doctor.

It is normally recommended for 3 days for dental pain, but if used for acute pain situations, it should be administered for as long as the discomfort lasts and no more than 8 days.

It is often given for long-term usage in the treatment of arthritis, however, this varies from person to person.


Precautions for using the Tzact medication

If any of the following symptoms arise or worsen: shortness of breath, chest pains, or ankle edema, discontinue Tzact medication and see a doctor as soon as possible.

Your doctor should keep an eye on you if you have renal, liver, or heart illnesses.

If you have any symptoms that might signal a severe allergic response, such as difficulty breathing or a severe skin reaction, you should see a doctor right away.

Your doctor will want to talk to you about your treatment from time to time. It is critical that you use the lowest effective dosage for your pain and that you do not use Tzact for any longer than required.

This is because the risk of heart attacks and strokes may grow with long-term therapy, particularly at high dosages.

Tzact may raise blood pressure in certain individuals, particularly when taken in large doses, which may increase the risk of heart attack and stroke.

Your doctor will want to monitor your blood pressure regularly to ensure that you can continue therapy safely.

Alcohol: It is not safe to drink alcohol while using the Tzact Tablet.

Pregnancy: Tzact tablets should not be used during pregnancy. Although there has been little human research, animal studies have shown detrimental consequences on the growing fetus.

Before prescribing it to you, your doctor will consider the advantages as well as any possible hazards. Please visit your physician.

Breast-feeding: There is no information available on the usage of the Tzact Tablet during nursing. Please visit your physician.

Driving: It is not safe for driving. Tzact Tablet may impair your awareness, impair your eyesight, or cause you to feel drowsy and dizzy. If you have any of these symptoms, do not drive.

Kidney or renal diseases: Tzact Tablet should be taken with care in persons suffering from renal disease, especially when severe. Tzact Tablet dosage may need to be adjusted. Please visit your physician.

Liver or hepatic diseases: Tzact Tablet should be taken with care in people suffering from liver disease, especially severe liver diseases. Tzact Tablet dosage may need to be adjusted. Please visit your physician.


Are there any drug interactions with the Tzact tablet?

Tzact may interact with any of the following medications, altering their effectiveness and causing unwanted side effects;

  • Warfarin
  • Oxyphenbutazone (Life-threatening) - Oxy Triactin, Sioril.
  • Methotrexate
  • Hormone Replacement Therapy
  • Nimesulide (Life-threatening) - Nimsun, Neil, Esulide.
  • Rifampin
  • Metamizole (Life-threatening) - Pyregin, Alpagin, Novalgin RC.
  • Oral Contraceptives
  • Aspirin tablet

Tzact may interact unfavorably with prescription and over-the-counter drugs, vitamins, and herbal supplements, so always check your doctor before taking any medications.


Is Tzact safe?

Yeah, it is, when taken as prescribed. To get the most out of it, take it exactly as directed. It is harmful to take more or for a longer period than is necessary.

Even a short-term therapy with the novel COX-2 inhibitor etoricoxib has the potential to produce renal failure and life-threatening hyperkalemia in certain people.

In general, you should take the lowest effective dosage for the shortest time.

Always make sure to consult your doctor before taking medications like this because they are certain conditions you might be in that taking Tzact will be very harmful to you. 

This will make it easier for you to go about your regular routines and have a better, more active quality of life.


Is Tzact tablet a controlled drug?

No, under the Prohibited Substances Act, Tzact is not a controlled drug.


Is the Tzact tablet available in a generic version?

No, they ain’t any generic versions of this drug as of now. Maybe later on in the future, the generic versions will be manufactured.


Alternatives or substitutes to Tzact tablet

  • Etos Tablet
  • Intacoxia Tablet
  • Etocox Tablet
  • Etosaid Tablet
  • Retoz Tablet
  • Etorica Tablet
  • Etoshine Tablet
  • Etrobax Tablet
  • Etody Tablet
  • Brutaflamn Tablet


What is the cost of the Tzact tablet?

Tzact costs range from $89.25 to $106.25 depending on the dose or strength you buy. Discount prices are available at some places at $18.75 (15%). 


Where can I buy a Tzact tablet?

It can be bought at your local pharmacy, hospitals, and online drug stores like Mediwapp, Medivik, and Dawaadost.


Storage of Tzact tablet?

Store away from direct sunlight at a temperature of under 30`C.


Final words on Tzact tablet by Healthsoothe

Tzact reduces pain and inflammation while posing a lower risk of stomach ulcers than NSAIDs.

Taking aspirin with Tzact, on the other hand, may negate this advantage (see Before you take Tzact, Taking Other Medicines).

If you are allergic to Tzact or any other drugs, consult your doctor before using it. The product will include inactive chemicals that may cause severe allergic reactions or other major issues.

Before using the drug, see your doctor if you have a history of asthma, allergies, stomach discomfort, inflammatory bowel disease, or any other cardiac issue.

Tzact had a decreased risk of ulcer development in clinical investigations than NSAIDs. In these trials, some persons had ulcers whether they were taking Tzact or a placebo; nevertheless, the incidence was greater with Tzact.

Tzact Tablet relieves pain and inflammation and may cause less gastrointestinal issues than other NSAIDs such as Ibuprofen or Naproxen.

It might make you dizzy and tired. Do not drive or do anything that requires concentration until you have determined how it affects you.

Avoid drinking alcohol while taking this medication since it may induce extreme sleepiness.

Keep a close eye on your blood pressure while taking this medication, especially in the first two weeks.

Tell your doctor if you've had stomach ulcers, heart problems, high blood pressure, or liver or kidney illness in the past.

Your doctor may order frequent blood tests to check your liver function throughout long-term therapy.

Do not use Tzact Tablet if you are pregnant, want to become pregnant, or are nursing.


Frequently Asked Questions about Tzact tablet 

Is Tzact safe for my kidneys?

Patients with compromised renal function, severe heart failure, or severe liver issues (liver cirrhosis) should exercise caution while using Tzact since the medication may further impair function.

Tzact renal adverse effects include protein in the urine, elevated serum creatinine, and kidney failure.

Even a short-term therapy with the novel COX-2 inhibitor etoricoxib has the potential to produce renal failure and life-threatening hyperkalemia in certain people.

So always make sure to consult your doctor first before taking certain medications.


Is Tzact superior to Naproxen?

Tzact is a very effective cyclooxygenase-2 (COX-2) inhibitor that is used to treat rheumatoid arthritis.

In a 12-week experiment, etoricoxib (90 mg once daily) was shown to be more effective than naproxen (500 mg twice daily) or placebo in treating rheumatoid arthritis.


Can I stop using Tzact when my pain has subsided?

If you are using Tzact Tablet for a disease that causes chronic pain, you should keep taking it as prescribed by your doctor. It may be stopped if you are just taking it for temporary pain relief.


Is it ok to use aspirin while taking Tzact?

When used to prevent strokes and heart attacks, aspirin may be taken at modest dosages. You should discontinue using low-dose aspirin without first seeing your doctor.

It is recommended that you avoid using aspirin and other anti-inflammatory medications while taking Tzact since they may raise your risk of stomach ulcers.


Does Tzact make you sleepy?

Tzact produces drowsiness, a spinning sensation (vertigo), and dizziness in some people. Driving or using types of equipment should be avoided if these symptoms are present.


Does Tzact interact with birth control pills?

Tzact may cause negative effects when used with birth control pills and hormone replacement treatment. As a result, see your doctor, who will recommend another form of birth control.

Editorial Review Ratings
Tzact is a powerful NSAID that can effectively reduce pain and inflammation caused by various conditions like arthritis and gout
Being prescription-only ensures proper diagnosis and dosage management by a doctor, minimizing misuse
The medication is available in tablet form, making it easy to administer orally, which is convenient and pain-free
Tzact isn't a controlled substance meaning that it has a lower potential for addiction compared to some pain medications
By targeting the COX-2 enzyme, Tzact may offer benefits beyond just pain relief, potentially reducing inflammation in certain conditions
Like most NSAIDs, Tzact can cause stomach upset, heartburn, nausea, and other gastrointestinal issues. More serious side effects are also possible
People with certain medical conditions or allergies may not be able to take Tzact safely
Tzact can interact with other medications, so it's crucial to disclose all medications you take to your doctor
Due to potential risks to the developing baby, Tzact is not recommended during pregnancy or breastfeeding
While Tzact reduces pain and inflammation, it doesn't address the root cause of the condition. Complementary therapies might be needed for long-term management

I Am odudu abasi a top-notch and experienced freelance writer, virtual assistant, graphics designer and a computer techie who is adept in content writing, copywriting, article writing, academic writing, journal writing, blog posts, seminar presentations, SEO contents, proofreading, plagiarism/AI checking, editing webpage contents/write-ups and WordPress management.My work mantra is: "I can, and I will"

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