Dicyclomine: Uses, Side Effects, Dosage & Reviews

Dicyclomine is prescribed for managing muscle spasms in the stomach and intestines in individuals who have irritable bowel syndrome (IBS). 

It's usually ingested orally, usually four times a day. Typical adverse effects encompass dizziness, parched mouth, and unclear eyesight. Senior citizens are more likely to encounter these side effects.

How to Use Dicyclomine

Dicyclomine functions as an anticholinergic agent. It operates by inhibiting the binding of a chemical known as acetylcholine to receptors located in the stomach and intestines. 

Normally, acetylcholine triggers contractions in the gut muscles. Through the inhibition of acetylcholine, dicyclomine induces relaxation in the stomach and intestines' muscles, thereby reducing cramps in individuals with IBS.

Dicyclomine is employed for treating a specific type of intestinal issue known as irritable bowel syndrome. It assists in alleviating symptoms of stomach and intestinal cramping. 

This medication operates by slowing down natural gut movements and relaxing stomach and intestinal muscles. Dicyclomine belongs to a category of drugs called anticholinergics/antispasmodics. 

However, it must not be used in children under 6 months old due to the risk of serious side effects.

To use Dicyclomine HCL:

  • Ingest the medication by mouth, with or without food, following your doctor's instructions, generally four times a day.
  • Your doctor may advise starting at a low dose and gradually increasing it to minimise side effects.
  • If you're using the liquid form, measure the dose using a proper measuring device/spoon, not a regular household spoon. Mix the liquid dose with an equal amount of water before consumption.
  • Don't take this medication simultaneously with antacids, as antacids can hinder dicyclomine absorption. If you're on an antacid, take it after meals, and dicyclomine before meals.
  • The dosage is determined by your age, medical condition, and how you respond to treatment.

How long does dicyclomine stay in your system?

Dicyclomine is an antispasmodic medication that is used to treat conditions such as irritable bowel syndrome (IBS) and certain gastrointestinal disorders. The duration that dicyclomine stays in your system can vary based on factors such as your metabolism, dosage, frequency of use, and individual differences.

The elimination half-life of dicyclomine is approximately 1.5 to 2.5 hours. This means that it takes this amount of time for the concentration of dicyclomine in your bloodstream to decrease by half. On average, it might take about 6 to 12 hours for dicyclomine to be mostly eliminated from your system.

However, it's important to note that individual variations can play a significant role. Some people might metabolize the drug faster or slower than others.

Additionally, the duration of effects (relief from spasms and discomfort) might differ from the time it takes for the drug to be fully eliminated from the body.

If you have concerns about how long dicyclomine might be present in your system, especially if you're considering taking other medications or have underlying medical conditions, it's recommended to consult a healthcare professional for personalized advice based on your specific circumstances.

What are the side effects of Dicyclomine?

Notify your medical professional promptly if you encounter any of the subsequent severe effects:

  • Coma
  • Profound alterations in mood, thoughts, or behaviour such as psychosis, restlessness, hallucinations (seeing or hearing nonexistent things), bewilderment, or intense elation
  • Irregular heartbeat manifested as fainting, dizziness or lightheadedness, chest discomfort, shortness of breath, or exhaustion

Additionally, the subsequent effects might improve as your body adjusts to the medication, but inform your healthcare provider promptly if they persist or worsen:

You might also experience side effects such as dizziness, drowsiness, lightheadedness, weakness, blurred vision, dry eyes, dry mouth, nausea, constipation, and abdominal bloating. If any of these effects persist or worsen, promptly inform your doctor or pharmacist.

For dry mouth, consider using sugarless hard candy, ice chips, sugarless gum, water, or a saliva substitute. Consult your pharmacist for advice on relieving dry eyes with artificial tears or other lubricants.

For highly serious side effects, seek medical assistance immediately. This includes symptoms like eye pain/swelling/redness or vision changes (such as seeing rainbows around lights at night).

While rare, a very serious allergic reaction can occur. Seek medical help promptly if you notice any indications of a severe allergic reaction, like rash, itching/swelling (particularly of the face/tongue/throat), intense dizziness, or breathing difficulties.


Drug interactions have the potential to alter the effectiveness of your medications or elevate the risk of severe side effects. 

This information is not exhaustive regarding all potential drug interactions. Maintain a record of all products you're using, which includes prescription/nonprescription drugs and herbal products. 

Share this list with your doctor and pharmacist. It's important not to initiate, discontinue, or modify the dosage of any medicine without the approval of your doctor. For more information, refer to the "How to Use" section.

Read Also: Ketorolac: Uses, Side Effects, Dosage & Reviews

Precautions and Dosages on how to take Dicyclomine 

Before using dicyclomine, ensure you inform your doctor or pharmacist if you are allergic to it or if you have any other allergies. 

This product might contain inactive components that could lead to allergic reactions or other complications. For further information, consult your pharmacist. 

As for dosing and usage instructions, take dicyclomine as directed by your doctor. Typically, it's taken by mouth, with or without food, usually four times a day. 

Your doctor might recommend starting with a low dose and gradually increasing it to reduce the risk of side effects. 

If you're using the liquid form, measure the dose carefully with a proper measuring device. Do not use a regular household spoon, as it might not provide the correct dose. Mixing the liquid dose with an equal amount of water before consumption might be necessary.

Additionally, refrain from taking this medication at the same time as antacids, as they can interfere with its absorption. If you're on an antacid, take it after meals, and take dicyclomine before meals.

It's crucial to follow your doctor's instructions precisely and maintain open communication about any concerns or questions you might have regarding the medication.


Dicyclomine is a medication utilised to address irritable bowel syndrome (IBS), a condition characterised by intestinal muscle spasms. 

By blocking the action of acetylcholine, a chemical that triggers muscle contractions in the stomach and intestines, dicyclomine helps alleviate symptoms like cramping. It belongs to the anticholinergic/antispasmodic class of drugs.

While taking dicyclomine, individuals might experience side effects such as dizziness, drowsiness, dry mouth, and blurred vision. 

These effects can often improve over time. It's crucial to report any severe or persistent side effects to a healthcare provider.

Dicyclomine can be a helpful solution for managing the symptoms of IBS, but its usage should be guided by a medical professional to ensure safety and effectiveness.

Wisdom Bassey
Wisdom Bassey
My name is Wisdom Bassey, I'm a blog content writer and graphic designer who provides support and services for brands and different companies. I'm young and versatile, A tech enthusiast. I carry out deep research on every topic I choose to write about. You can reach me through my social media handles, I'm always available and ready to connect.

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